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A COhort to study BLAdder CancEr

France, 2012
Reference ID
FRESH-PEF3096-en
Producer(s)
Maryam Karimi
Metadata
DDI/XML JSON
Created on
Nov 15, 2025
Last modified
Nov 15, 2025
Page views
3
  • Identification
  • Scope
  • Coverage
  • Producers and sponsors
  • Study authorization
  • Sampling
  • Survey instrument
  • Data collection
  • Study activities
  • Data Access
  • Contacts
  • Metadata production

    • Identification

    Survey ID number

    FRESH-PEF3096-en
    Title

    A COhort to study BLAdder CancEr
    Abbreviation or Acronym

    COBLAnCE
    Country
    Name
    France
    Abstract
    1. To test the association between constitutional DNA polymorphism, environmental parameters, molecular subtype and clinical data. The inclusion of features of both the tumour and the host will facilitate the discovery of tumourigenesis mechanisms, drugable targets and diagnostic and prognostic biomarkers. 2) To provide insight into the tumour progression knowledge and to help to identify biomarkers by the sequential sampling of recurrent tumors, plasma or urine from individual patients during follow_up. 3) To validate and extend our prior results regarding the molecular subtyping of bladder cancer on a large series of tumors collected prospectively. 4) To facilitate the transfer of study results into clinical practice thanks to the size and bladder cancer representativeness of the cohort. 5) To describe treatment patterns and to assess the direct and indirect costs of bladder cancer. The cost variability will be analyzed to identify the determinants of cost. This evaluation will pave the way for cost-benefit analyses of new biomarkers developed by the consortium. 6) To structure, at the national level, an interdisciplinary bladder cancer network including epidempiologists, bioinformaticians, health economists, molecular biologists, occupational physicians, pathologists and urologists, for coordinated and synergistic research actions and to make a significant contribution to a European multinational cohort and support international studies in genomics, in particular.
    Kind of Data

    ['Clinical data','Participant-reported health data','Biological data','Socio-demographic data']
    Unit of Analysis

    Individuals

    Scope

    Topics
    Topic Vocabulary URI
    Oncology health theme
    cim-11 http://id.who.int/icd/entity/765321840
    Behavioral determinants: Addiction health determinant
    Biological determinants: Genetic predisposition health determinant
    Behavioral determinants health determinant
    Behavioral determinants: Eating habits health determinant
    Healthcare system determinants: Use of care health determinant
    Socio-demographic and economic determinants: Employment health determinant
    Biological determinants health determinant
    Healthcare system determinants health determinant
    Socio-demographic and economic determinants health determinant
    Keywords
    Bladder cancer urology cancer research cohort

    Coverage

    Universe

    {
    "level_sex_clusion_I": [
    "Male",
    "Female"
    ],
    "level_age_clusion_I": [
    "Young Adult (19 to 24 years)",
    "Adult (25 to 44 years)",
    "Middle Aged (45 to 64 years)",
    "Aged (65 to 79 years)",
    "Aged, 80 and over (80 years and more)"
    ],
    "level_type_clusion_I": [
    "Patients population"
    ],
    "level_type_clusion_other": "",
    "clusion_I": "",
    "clusion_E": ""
    }

    Producers and sponsors

    Primary investigators
    Name
    Maryam Karimi
    Producers
    Name Role
    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) sponsor
    Funding Agency/Sponsor
    Name
    AGENCE NATIONALE DE LA RECHERCHE (ANR)

    Study authorization

    Agency
    Agency name
    CNIL
    CPP

    Sampling

    Sample frame

    Unit Type

    ['Through organizations (health services or institutions, schools, businesses, etc.)']
    Sampling Procedure

    ['Other']

    Survey instrument

    Questionnaires

    Access on specific project only
    Methodology notes

    Observational Study

    Data collection

    Dates of Data Collection
    Start
    2012
    Time Method

    Longitudinal or cohort study
    Mode of data collection
    • Self-administered questionnaire

    Study activities

    Study activities
    Type
    primary evaluation
    Description
    Health event/mortality Health care consumption and services Quality of life/health perception Others

    Data Access

    Availability Status

    Restricted access

    Contacts

    Contacts
    Name Email
    Maryam Karimi maryam.karimi@gustaveroussy.fr
    Karine Groussard karine.groussard@inserm.fr

    Metadata production

    DDI Document ID

    FRESH-PEF3096-en
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