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Autonomic maturation in neonatal period and early neurologic development: perspective longitudinal cohort study

France, 2009 - 2013
Reference ID
FRESH-PEF3658-en
Producer(s)
Georges Teyssier, Jean-Claude Barthélémy, Hugues Patural
Metadata
DDI/XML JSON
Created on
Nov 15, 2025
Last modified
Nov 15, 2025
Page views
3
  • Study Description
  • Get Microdata
  • Identification
  • Scope
  • Coverage
  • Producers and sponsors
  • Study authorization
  • Sampling
  • Survey instrument
  • Data collection
  • Study activities
  • Quality standards
  • Data Access
  • Contacts
  • Metadata production
  • Identification

    Survey ID number

    FRESH-PEF3658-en

    Title

    Autonomic maturation in neonatal period and early neurologic development: perspective longitudinal cohort study

    Abbreviation or Acronym

    AUBE

    Country
    Name
    France
    Abstract

    Describe the profile of maturation of the autonomic cardiac system (through time and frequency analysis of the heart rate variability from polysomnographic 24 hours records) during the firsts two years of life (0, 6, 12, 18 and 24 months) in a full-term or premature infants cohort. Secondary objectives: - Correlate in this cohort the autonomic status at birth and the neurological psychomotor becoming at 2 years; - Describe autonomic evolution profile during the firsts two years of life; - According to specific pregnancy criteria; - According to morphometry data; - According to respiratory, cardiac, neurological, digestive, infectious neonatal morbidity criteria; - According to the incidence of severe diseases and rhythmic disorders during the two firsts two years of life.

    Kind of Data

    ['Clinical data','Participant-reported health data','Paraclinical data (non-biological) : Function testing']

    Unit of Analysis

    Individuals

    Scope

    Topics
    Topic Vocabulary URI
    Neurology health theme
    Paediatrics health theme
    cim-11 http://id.who.int/icd/entity/1482041278
    cim-11 http://id.who.int/icd/entity/469631867

    Coverage

    Geographic Coverage

    ['Auvergne Rhône-Alpes']

    Universe

    {
    "level_sex_clusion_I": [
    "Male",
    "Female"
    ],
    "level_age_clusion_I": [],
    "level_type_clusion_I": [
    "General population"
    ],
    "level_type_clusion_other": "",
    "clusion_I": "",
    "clusion_E": ""
    }

    Producers and sponsors

    Primary investigators
    Name
    Georges Teyssier
    Jean-Claude Barthélémy
    Hugues Patural
    Producers
    Name Role
    CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT-ETIENNE sponsor
    Funding Agency/Sponsor
    Name
    MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES

    Study authorization

    Agency
    Agency name
    CNIL

    Sampling

    Sample frame

    Unit Type

    ['Through organizations (health services or institutions, schools, businesses, etc.)']

    Sampling Procedure

    ['Other']

    Survey instrument

    Questionnaires

    Access on specific project only

    Methodology notes

    Observational Study

    Data collection

    Dates of Data Collection
    Start End
    2009 2013
    Time Method

    Longitudinal or cohort study

    Mode of data collection
    • Self-administered questionnaire
    • Interview with the participant (including clinical)

    Study activities

    Study activities
    Study activities
    Type
    primary evaluation
    Description
    Health event/morbidity Health event/mortality

    Quality standards

    Other quality statement

    Coherence request after computer data entry. Missing data asked back to the patient or a third. Doctors remainders for follow-up visits. Internal quality audit reports every 6 months. Internal audit frequency: Statistics, by data themes. External audit frequency: 3. EIG declaration (serious adverse effects). Patients receive information about the use of their data.

    Data Access

    Availability Status

    Restricted access

    Restrictions

    Data utilization for academic teams and for industrials to be determined.

    Contacts

    Contacts
    Name Email
    Georges Teyssier georges.teyssier@chu-st-etienne.fr
    Hugues Patural hugues.patural@chu-st-etienne.fr

    Metadata production

    DDI Document ID

    FRESH-PEF3658-en

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