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Asthma and Airway Obstruction Cohort: Clinicobiological Cohort Follow-up

France, 2008 - 2018
Reference ID
FRESH-PEF60115-en
Producer(s)
Michel Aubier
Metadata
DDI/XML JSON
Created on
Nov 15, 2025
Last modified
Nov 15, 2025
Page views
4
  • Identification
  • Scope
  • Coverage
  • Producers and sponsors
  • Study authorization
  • Sampling
  • Survey instrument
  • Data collection
  • Study activities
  • Data Access
  • Contacts
  • Metadata production

    • Identification

    Survey ID number

    FRESH-PEF60115-en
    Title

    Asthma and Airway Obstruction Cohort: Clinicobiological Cohort Follow-up
    Abbreviation or Acronym

    COBRA
    Country
    Name
    France
    Abstract

    General objective: to establish a biological resource centre (serum, DNA) for two cohorts of patients with asthma and COBP monitored over a 10 year period. Secondary objective: to discover biological markers of severity (using proteomics technology) and genetic risk factors (by genomic-based approaches) associated with the evolution of these pathologies.
    Kind of Data

    ['Clinical data','Participant-reported health data','Biological data','Paraclinical data (non-biological) : Imaging']
    Unit of Analysis

    Individuals

    Scope

    Topics
    Topic Vocabulary URI
    Pulmonary medicine health theme
    cim-11 http://id.who.int/icd/entity/1294329406
    Environmental determinants: Climate health determinant
    Environmental determinants health determinant
    Keywords
    Health episodes severity

    Coverage

    Universe

    {
    "level_sex_clusion_I": [
    "Male",
    "Female"
    ],
    "level_age_clusion_I": [
    "Young Adult (19 to 24 years)",
    "Adult (25 to 44 years)",
    "Middle Aged (45 to 64 years)",
    "Aged (65 to 79 years)"
    ],
    "level_type_clusion_I": [
    "Patients population"
    ],
    "level_type_clusion_other": "",
    "clusion_I": "",
    "clusion_E": ""
    }

    Producers and sponsors

    Primary investigators
    Name
    Michel Aubier
    Producers
    Name Role
    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) sponsor
    Funding Agency/Sponsor
    Name
    ASTRAZENECA (FRANCE)
    CHIESI (FRANCE)
    GLAXOSMITHKLINE (FRANCE)
    CENTRE HOSPITALIER UNIVERSITAIRE DE NIMES (CHU)
    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

    Study authorization

    Agency
    Agency name
    CNIL

    Sampling

    Sample frame

    Unit Type

    ['Through organizations (health services or institutions, schools, businesses, etc.)']
    Sampling Procedure

    ['Other']

    Survey instrument

    Questionnaires

    Access on specific project only
    Methodology notes

    Observational Study

    Data collection

    Dates of Data Collection
    Start End
    2008 2018
    Time Method

    Longitudinal or cohort study
    Mode of data collection
    • Self-administered questionnaire
    • Interview with the participant (including clinical)

    Study activities

    Study activities
    Type
    primary evaluation
    Description
    Health event/morbidity Health event/mortality Quality of life/health perception

    Data Access

    Access conditions

    Contractual access subject to COBRA Scientific Council validation. Research projects that can use clinical and/or biological cohort data are encouraged and validated by the Scientific Council (2 members per centre).
    Availability Status

    Restricted access
    Restrictions

    Data may be used by academic teams. Data may not be used by industrial teams.

    Contacts

    Contacts
    Name Email
    Michel Aubier michel.aubier@wanadoo.fr

    Metadata production

    DDI Document ID

    FRESH-PEF60115-en
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