FRESH-PEF74087-en
A Cohort Study of Patients With Metastatic Colorectal Cancer Treated With Avastin® as First-line Therapy for Liver Metastases Considered as Potentially Resectable
PICASSO
| Name |
|---|
| France |
Primary Objective: evaluate the efficacy and safety of bevacizumab as first-line treatment in participants with colorectal cancer and potentially resectable liver metastases. Secondary Objectives: - To describe patients’ characteristics treated with Avastin®, - To describe the subgroup of patients with unresected missing metastases, with or without surgery, - To describe criteria used to define unresectability, - To describe progression-free survival in all patients, - To describe relapse-free survival in all resected patients with no DMD, - To describe overall survival in all patients, - To describe histopathological response in resected patients, - To describe Avastin® treatment modalities, - To describe safety profile of Avastin®.
['Clinical data','Participant-reported health data']
Individuals
| Topic | Vocabulary | URI |
|---|---|---|
| Gastroenterology | health theme | |
| cim-11 | http://id.who.int/icd/entity/1331250723 | |
| Healthcare system determinants: Use of care | health determinant | |
| Healthcare system determinants | health determinant |
{
"level_sex_clusion_I": [
"Male",
"Female"
],
"level_age_clusion_I": [
"Young Adult (19 to 24 years)",
"Adult (25 to 44 years)",
"Middle Aged (45 to 64 years)",
"Aged (65 to 79 years)",
"Aged, 80 and over (80 years and more)"
],
"level_type_clusion_I": [
"Patients population"
],
"level_type_clusion_other": "",
"clusion_I": "",
"clusion_E": ""
}
| Name | Role |
|---|---|
| F. HOFFMANN-LA ROCHE AG | sponsor |
| Agency name |
|---|
| Autre |
['Through independent healthcare practitioners']
['Other']
Access on specific project only
Observational Study
| Start | End |
|---|---|
| 2010 | 2015 |
Longitudinal or cohort study
| Standard |
|---|
| ['CDISC like'] |
GCP/GVP
Restricted access
| Name | |
|---|---|
| Medical data center | data_sharing.france@roche.com |
FRESH-PEF74087-en