{"doc_desc":{"title":"Cohorte \"Vingt mille volontaires pour la recherche m\u00e9dicale\"","idno":"FRESH-PEF3476-fr","producers":[{"name":"Marcel GOLDBERG","affiliation":"UNIVERSITE PARIS-SACLAY"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF3476-fr","IDno":{"metadata_no":[{"agency":"PEF","code":"3476"},{"agency":"FReSH","code":"FRESH-PEF3476"}]},"title":"Cohorte \"Vingt mille volontaires pour la recherche m\u00e9dicale\"","alternate_title":"GAZEL"},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"type":"investigator","name":"Marie;ZINS","PILabo":"Paris Saclay University, University of Paris, Versailles University, INSERM \/ UMS 011 : Cohortes \u00e9pid\u00e9miologiques en population","affiliationName":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","extlink":[{"title":"ORCID","uri":"0000-0002-4540-4282","role":"pi id"},{"title":"IdRef","uri":"074613324","role":"pi id"},{"title":"SIREN","uri":"180036048","role":"organisation id"},{"title":"RNSR","uri":"201322808P","role":"labo id"}],"email":"marie.zins@inserm.fr","isContact":"Oui"},{"type":"investigator","name":"Marcel;GOLDBERG","PILabo":"","affiliationName":"UNIVERSITE PARIS-SACLAY","extlink":[{"title":"ORCID","uri":"0000-0002-6161-5880","role":"pi id"},{"title":"IdRef","uri":"028740637","role":"pi id"},{"title":"SIREN","uri":"130026024","role":"organisation id"},{"title":"RNSR","uri":"201420731C","role":"labo id"}],"email":"marcel.goldberg@inserm.fr","isContact":"Oui"}],"oth_id":[{"name":"Consortiums et collaborations :- IDEAR (Integrated Datasets across Europe for Ageing Research)- LIFEPATH-OMEGA-NET-EPHOR","type":"collaboration"}],"production_statement":{"prod_place":"Portail Epid\u00e9miologie France (PEF)","producers":[{"name":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/02vjkv261","role":"sponsor id"},{"title":"SIREN","uri":"180036048","role":"sponsor id"}],"role":"sponsor"}],"funding_agencies":[{"name":"GIS-INSTITUT POUR LA RECHERCHE EN SANTE PUBLIQUE (IRESP)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/05fw72335"}]},{"name":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/02vjkv261"},{"title":"SIREN","uri":"180036048"}]},{"name":"CCAS","extlink":[]},{"name":"CNAM","extlink":[]},{"name":"CMCAS","extlink":[]}]},"distribution_statement":{"contact":[{"name":"Marie;ZINS","email":"marie.zins@inserm.fr","type":"contact","affiliationName":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/02vjkv261","role":"organisation id","title":"ROR"},{"uri":"180036048","role":"organisation id","title":"SIREN"}]},{"name":"Marcel;GOLDBERG","email":"marcel.goldberg@inserm.fr","type":"contact","affiliationName":"UNIVERSITE PARIS-SACLAY","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/03xjwb503","role":"organisation id","title":"ROR"},{"uri":"130026024","role":"organisation id","title":"SIREN"}]}]},"study_info":{"keywords":[{"keyword":"Cohorte g\u00e9n\u00e9raliste"},{"keyword":"d\u00e9terminants sociaux"},{"keyword":"adultes"},{"keyword":"vieillissement"},{"keyword":"risques professionnels"}],"topics":[{"topic":"COVID-19","vocab":"cim-11","extLink":[{"uri":"http:\/\/id.who.int\/icd\/entity\/1730556128","title":"CIM-11"}]},{"topic":"D\u00e9terminants socio-d\u00e9mographiques et \u00e9conomiques","vocab":"health determinant"},{"topic":"D\u00e9terminants biologiques : Pr\u00e9dispositions g\u00e9n\u00e9tiques","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux : Autres","vocab":"health determinant"},{"topic":"D\u00e9terminants comportementaux","vocab":"health determinant"},{"topic":"D\u00e9terminants comportementaux : Alimentation","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux","vocab":"health determinant"},{"topic":"D\u00e9terminants li\u00e9s au syst\u00e8me de sant\u00e9 : Consommation des soins","vocab":"health determinant"},{"topic":"Syst\u00e8mes de soins et acc\u00e8s aux soins","vocab":"health determinant"},{"topic":"D\u00e9terminants socio-d\u00e9mographiques et \u00e9conomiques : Emploi","vocab":"health determinant"},{"topic":"D\u00e9terminants biologiques","vocab":"health determinant"},{"topic":"D\u00e9terminants li\u00e9s au syst\u00e8me de sant\u00e9","vocab":"health determinant"}],"purpose":"Mise en place en 1989, cette cohorte est compos\u00e9e de 20 625 agents d\u2019EDF-GDF \u00e2g\u00e9s de 35 \u00e0 50 ans \u00e0 l\u2019origine. Elle a \u00e9t\u00e9 con\u00e7ue pour \u00eatre ouverte \u00e0 la communaut\u00e9 scientifique. Les donn\u00e9es font l\u2019objet d\u2019un recueil syst\u00e9matique aupr\u00e8s de diff\u00e9rentes sources. Une banque de mat\u00e9riel biologique a \u00e9t\u00e9 constitu\u00e9e. Apr\u00e8s plus de 22 ans de suivi, plus d\u2019une quarantaine de projets de recherche, concernant des sujets aussi divers que la migraine, l\u2019ost\u00e9oporose, les maladies cardiovasculaires, la d\u00e9pression, les troubles musculo-squelettiques, ou les accidents de la route ont \u00e9t\u00e9 mis en place par une trentaine d\u2019\u00e9quipes fran\u00e7aises et \u00e9trang\u00e8res (Allemagne, Belgique, Canada, Grande-Bretagne, Su\u00e8de, Finlande, USA). Dans les prochaines ann\u00e9es, les orientations scientifiques concerneront plus particuli\u00e8rement l\u2019\u00e9tude du vieillissement (effets \u00e0 long terme des expositions professionnelles, vieillissement cognitif et fonctionnel pr\u00e9matur\u00e9, troubles musculosquelettiques et qualit\u00e9 de vie, in\u00e9galit\u00e9s sociales de sant\u00e9 chez les personnes \u00e2g\u00e9es).","abstract":"","coll_dates":[{"start":"1989-01-01","end":"2024-01-01"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"Masculin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008297\"\n            }\n        },\n        {\n            \"value\": \"F\u00e9minin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Adulte (45 \u00e0 64 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008875\"\n            }\n        },\n        {\n            \"value\": \"Personne \u00e2g\u00e9e (65 \u00e0 79 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000368\"\n            }\n        },\n        {\n            \"value\": \"Grand \u00e2ge (80 ans et plus)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000369\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Population g\u00e9n\u00e9rale\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"Agents EDF-GDF \u00e2g\u00e9s de 35 \u00e0 50 ans en 1989.\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Donn\u00e9es rapport\u00e9es par le participant de l'\u00e9tude','Donn\u00e9es paracliniques','Donn\u00e9es biologiques','Donn\u00e9es socio-d\u00e9mographiques','Donn\u00e9es paracliniques (hors biologiques) : Anthropom\u00e9trie','Donn\u00e9es paracliniques (hors biologiques) : Autre']","quality_statement":{"standards":[{"name":"['CIM 10, CCAM, ATC']","committee":"","governance":""}],"other_quality_statement":""}},"study_development":{"development_activity":[{"activity_type":"primary evaluation","activity_description":"Ev\u00e9nements de sant\u00e9\/morbidit\u00e9\r\nEv\u00e9nements de sant\u00e9\/mortalit\u00e9\r\nConsommation de soins\/services de sant\u00e9\r\nQualit\u00e9 de vie\/sant\u00e9 per\u00e7ue"}]},"method":{"data_collection":{"time_method":"","frequency":"","sampling_procedure":"['{\"concept\":{\"vocabURI\":\"Other\",\"vocab\":\"CESSDA\"},\"value\":\"Autre\"}']","sample_frame":{"frame_unit":{"unit_type":"['Base de population \u00e0 finalit\u00e9 statistique Base administrative (d'employ\u00e9s, d'\u00e9l\u00e8ves, d'\u00e9tudiants, etc\u2026)']"}},"coll_mode":["{\"concept\":{\"vocabURI\":\"SelfAdministeredQuestionnaire\",\"vocab\":\"CESSDA\"},\"value\":\"Questionnaire auto-administr\u00e9\"}"],"research_instrument":"Acc\u00e8s libre","sources":[{"sourceCitation":{"titlStmt":{"titl":""},"holdings":"","notes":{"subject":"source purpose","value":""}},"srcOrig":["Base m\u00e9dico-administrative"]}],"target_sample_size":">= 20000 individus","response_rate":"20 625"},"method_notes":"Etude observationnelle","study_class":"Inconnu","notes":[{"subject":"research type","values":["Etude observationnelle"]},{"subject":"observational study method","values":["Cohorte"]}]},"data_access":{"dataset_availability":{"access_place":"","complete":"","status":"{\"value\":\"Acc\u00e8s r\u00e9serv\u00e9\",\"extLink\":[{\"title\":\"COAR\",\"uri\":\"http:\/\/purl.org\/coar\/access_right\/c_16ec\"}]}"},"dataset_use":{"restrictions":"","conditions":"","conf_dec":[{"txt":""}],"spec_perm":[{"txt":"","required":""}],"contact":[{"name":""}],"deposit_req":"","cit_req":""},"notes":"Appel \u00e0 projet de recherche permanent Catalogue des donn\u00e9es de la cohorte disponible sur le site web d\u00e9di\u00e9 Charte d'acc\u00e8s"}},"additional":{"IsImport":true,"versionLang":"fr","originLang":"fr","autoTranslation":false,"status":"imported","creationDate":"25-04-2012","lastUpdatedAuto":null,"lastUpdatedManual":"01-10-2021","isContributorPI":"Non","contributorName":"Marcel GOLDBERG","contributorAffiliation":"UNIVERSITE PARIS-SACLAY","addTeamMember":"","obtainedAuthorization":{"otherAuthorizingAgency":[""]},"relatedDocument":[],"regulatoryRequirements":{"conformityDeclaration":""},"fundingAgent":{"fundingAgentType":["Public (France)","Public (France)","Autre","Public (France)","Autre"],"otherFundingAgentType":["","","","",""]},"sponsor":{"sponsorType":["Public (France)"],"otherSponsorType":[""]},"governance":{"committee":"Oui"},"collaborations":{"networkConsortium":"Oui"},"theme":{"complementaryInformation":"","RareDiseases":""},"activeFollowUp":{"isActiveFollowUp":"Oui","followUpModeOther":""},"interventionalStudy":{"researchPurpose":[],"trialPhase":[],"interventionalStudyModel":"","isClinicalTrial":"","otherResearchPurpose":""},"isInclusionGroups":"","allocation":{"allocationMode":"","allocationUnit":""},"masking":{"maskingType":"","blindedMaskingDetails":[]},"arms":[],"intervention":[],"inclusionGroups":[],"collectionProcess":{"collectionModeDetails":"Autoquestionnaire postal annuel, Suivi dans des bases de donn\u00e9es : les principaux \u00e9v\u00e9nements socioprofessionnels proviennent des services du personnel. Les donn\u00e9es de sant\u00e9 concernent le statut vital et les causes de d\u00e9c\u00e8s du C\u00e9piDc-Inserm ; les principaux \u00e9v\u00e9nements de sant\u00e9 sont extraits du Syst\u00e8me national d\u2019information inter r\u00e9gimes de l\u2019assurance maladie (SNDS) : donn\u00e9es de remboursement, Affections de longue dur\u00e9e (ALD), et pour chacun des s\u00e9jours hospitaliers : diagnostic principal et diagnostics associ\u00e9s, actes diagnostiques et th\u00e9rapeutiques.","collectionModeOther":""},"dataCollection":{"inclusionStrategyOther":"","samplingModeOther":"","recruitmentSourceOther":"","otherDocumentation":""},"dataCollectionIntegration":{"isDataIntegration":"Oui"},"geographicalCoverage":{"geoDetail":"France enti\u00e8re"},"dataTypes":{"clinicalDataDetails":"","biologicalDataDetails":"R\u00e9gulation glyc\u00e9mique, bilan lipidique, bilan h\u00e9patique, cr\u00e9atin\u00e9mie, num\u00e9ration formule sanguine, examen urinaire.","isDataInBiobank":"Oui","biobankContent":[],"biobankContentOther":"","dataTypeOther":""},"variableDictionnary":{"variableDictionnaryAvailable":"","variableDictionnaryLink":""},"dataQuality":{"otherDocumentation":""},"mockSample":{"mockSampleAvailable":"","mockSampleLocation":""},"thirdPartySource":{"otherSourceType":[""]},"isHealthTheme":"Non","fileDscr":{"fileTxt":{"fileCitation":{"titlStmt":{"IDno":[]}}}}},"schematype":"survey"}