{"doc_desc":{"title":"Longitudinal study of patients with high-grade locally developed Fallopian tube-ovarian epithelial cancer","idno":"FRESH-PEF38974-en","producers":[{"name":"Pierre-Emmanuel COLOMBO","affiliation":"INSTITUT REGIONAL DU CANCER DE MONTPELLIER (ICM)"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF38974-en","IDno":{"metadata_no":[{"agency":"PEF","code":"38974"},{"agency":"FReSH","code":"FRESH-PEF38974"}]},"title":"Longitudinal study of patients with high-grade locally developed Fallopian tube-ovarian epithelial cancer","alternate_title":"KOv"},"study_authorization":{"agency":[]},"authoring_entity":[{"type":"investigator","name":"Pierre-Emmanuel;COLOMBO","PILabo":"Montpellier Cancer Institute \/ Oncological surgery","affiliationName":"INSTITUT REGIONAL DU CANCER DE MONTPELLIER (ICM)","extlink":[{"title":"ORCID","uri":"0000-0002-0697-109X","role":"pi id"},{"title":"IdRef","uri":"111884888","role":"pi id"},{"title":"SIREN","uri":"788214963","role":"organisation id"},{"title":"","uri":"","role":"labo id"}],"email":"pierre-emmanuel.colombo@icm.unicancer.fr","isContact":"Yes"}],"oth_id":[{"name":""}],"production_statement":{"prod_place":"Epidemiology France Portal (PEF)","producers":[{"name":"INSTITUT REGIONAL DU CANCER DE MONTPELLIER (ICM)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/00mrq0n58","role":"sponsor id"},{"title":"SIREN","uri":"788214963","role":"sponsor id"}],"role":"sponsor"}],"funding_agencies":[{"name":"INSTITUT REGIONAL DU CANCER DE MONTPELLIER (ICM)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/02693j602"},{"title":"SIREN","uri":"788214963"}]}]},"distribution_statement":{"contact":[{"name":"Pierre-Emmanuel;COLOMBO","email":"pierre-emmanuel.colombo@icm.unicancer.fr","type":"contact","affiliationName":"INSTITUT REGIONAL DU CANCER DE MONTPELLIER (ICM)","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/02693j602","role":"organisation id","title":"ROR"},{"uri":"788214963","role":"organisation id","title":"SIREN"}]}]},"study_info":{"keywords":[{"keyword":"BRCA status"},{"keyword":"FIGO stage"},{"keyword":"genetic analysis"},{"keyword":"Cancer"},{"keyword":"treatment"},{"keyword":"mortality"},{"keyword":"survival"},{"keyword":"prognosis"}],"topics":[{"topic":"Oncology","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/5784b7f1-c7ce-49d9-9f38-aebcda0ff41d"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D008495"}]},{"topic":"Gynaecology and obstetrics","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/7de64596-5b0d-4977-8f98-b982ff2ec17d"},{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/284ca20c-beb4-4abe-99fa-ef4513358bad"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D006176"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D009774"}]},{"topic":"Biological determinants: Genetic predisposition","vocab":"health determinant"},{"topic":"Healthcare system determinants: Use of care","vocab":"health determinant"},{"topic":"Biological determinants","vocab":"health determinant"},{"topic":"Healthcare system determinants","vocab":"health determinant"}],"purpose":"The research project is a multidisciplinary project combining statistical methodology and clinical expertise using the KOv database. First of all, the purpose is to augment the database by increasing the genetic test results for the BRCA1 and BRCA2 genes in the population and updating the survival data. Two other major objectives for the use of data from the KOv database: To determine estimates of conditional probabilities of survival in our patient population. To identify factors that may inform the prognosis among a long-surviving patient population, i.e. patients alive 4 years after diagnosis.","abstract":"","coll_dates":[{"start":"1995-01-01","end":"2014-01-01"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"['Occitanie']","analysis_unit":"Individuals","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"Female\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Young Adult (19 to 24 years)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D055815\"\n            }\n        },\n        {\n            \"value\": \"Adult (25 to 44 years)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000328\"\n            }\n        },\n        {\n            \"value\": \"Middle Aged (45 to 64 years)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008875\"\n            }\n        },\n        {\n            \"value\": \"Aged (65 to 79 years)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000368\"\n            }\n        },\n        {\n            \"value\": \"Aged, 80 and over (80 years and more)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000369\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Patients population\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"Patients with high-grade locally developed Fallopian tube-ovarian epithelial cancer treated at ICM\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Clinical data','Biological data']","quality_statement":{"standards":[{"name":"","committee":"","governance":""}],"other_quality_statement":""}},"study_development":{"development_activity":[{"activity_type":"primary evaluation","activity_description":"Health event\/morbidity\r\nHealth event\/mortality\r\nHealth care consumption and services\r\nQuality of life\/health perception"}]},"method":{"data_collection":{"time_method":"","frequency":"","sampling_procedure":"['{\"concept\":{\"vocabURI\":\"Other\",\"vocab\":\"CESSDA\"},\"value\":\"Other\"}']","sample_frame":{"frame_unit":{"unit_type":"['Through organizations (health services or institutions, schools, businesses, etc.)']"}},"coll_mode":["{\"concept\":{\"vocabURI\":\"Other\",\"vocab\":\"CESSDA\"},\"value\":\"Other\"}"],"research_instrument":"Access on specific project only","sources":[],"target_sample_size":"< 500 individuals","response_rate":"470"},"method_notes":"Observational Study","study_class":"Unknown","notes":[{"subject":"research type","values":["Observational Study"]}]},"data_access":{"dataset_availability":{"access_place":"","complete":"","status":"{\"value\":\"Restricted access\",\"extLink\":[{\"title\":\"COAR\",\"uri\":\"http:\/\/purl.org\/coar\/access_right\/c_16ec\"}]}"},"dataset_use":{"restrictions":"","conditions":"Contact the principal investigator","conf_dec":[{"txt":""}],"spec_perm":[{"txt":"","required":""}],"contact":[{"name":""}],"deposit_req":"","cit_req":""},"notes":""}},"additional":{"IsImport":true,"versionLang":"en","originLang":"en","autoTranslation":false,"status":"imported","creationDate":"31-03-2015","lastUpdatedAuto":null,"lastUpdatedManual":"12-09-2017","isContributorPI":"No","contributorName":"Pierre-Emmanuel COLOMBO","contributorAffiliation":"INSTITUT REGIONAL DU CANCER DE MONTPELLIER 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