{"doc_desc":{"title":"Cohorte logifer : patients ayant une h\u00e9mochromatose HFE (homozygote C282Y)","idno":"FRESH-PEF5027-fr","producers":[{"name":"Edouard BARDOU-JACQUET","affiliation":"CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF5027-fr","IDno":{"metadata_no":[{"agency":"PEF","code":"5027"},{"agency":"FReSH","code":"FRESH-PEF5027"}]},"title":"Cohorte logifer : patients ayant une h\u00e9mochromatose HFE (homozygote C282Y)","alternate_title":"LOGIFER"},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"type":"investigator","name":"Edouard;BARDOU-JACQUET","PILabo":"CENTRE HOSPITALIER UNIVERSITAIRE DE \/ CIC INSERM 0203","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES","extlink":[{"title":"ORCID","uri":"0000-0002-0784-0710","role":"pi id"},{"title":"IdRef","uri":"115637389","role":"pi id"},{"title":"ROR","uri":"https:\/\/ror.org\/05qec5a53","role":"organisation 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theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/27c456a1-051a-42f6-b52a-3beff0487da7"}]},{"topic":"D\u00e9terminants biologiques : Pr\u00e9dispositions g\u00e9n\u00e9tiques","vocab":"health determinant"},{"topic":"D\u00e9terminants biologiques","vocab":"health determinant"}],"purpose":"Suivi de tous les patients ayant une h\u00e9mochromatose HFE (homozygote C282Y) au CHU de Rennes dans le but d'\u00e9tudier les facteurs d\u00e9terminants la s\u00e9v\u00e9rit\u00e9 de la maladie initiale, les facteurs influen\u00e7ant la mortalit\u00e9 et la morbidit\u00e9, les facteurs pr\u00e9dictifs de qualit\u00e9 du traitement d\u00e9pl\u00e9tif.","abstract":"","coll_dates":[{"start":"1990-01-01"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"Masculin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008297\"\n            }\n        },\n        {\n            \"value\": \"F\u00e9minin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Adulte (19 \u00e0 24 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D055815\"\n            }\n        },\n        {\n            \"value\": \"Adulte (25 \u00e0 44 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000328\"\n            }\n        },\n        {\n            \"value\": \"Adulte (45 \u00e0 64 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008875\"\n            }\n        },\n        {\n            \"value\": \"Personne \u00e2g\u00e9e (65 \u00e0 79 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000368\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Patients\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"patients ayant une h\u00e9mochromatose HFE (homozygote C282Y)\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Donn\u00e9es cliniques','Donn\u00e9es paracliniques','Donn\u00e9es biologiques','Donn\u00e9es socio-d\u00e9mographiques','Donn\u00e9es paracliniques (hors biologiques) : Imagerie','Donn\u00e9es paracliniques (hors biologiques) : Exploration 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