{"doc_desc":{"title":"Cohorte de sujets \u00e2g\u00e9s de 42 \u00e0 89 ans (en 2012)\/\u00e9tude du vieillissement c\u00e9r\u00e9bral et cardiovasculaire --> Evaluation de l\u2019impact des manifestations psycho-comportementales li\u00e9es au confinement lors de la pand\u00e9mie COVID-19 sur l\u2019aggravation des facteurs de risque cardiovasculaire et la d\u00e9compensation des maladies cardiovasculaires, en population g\u00e9n\u00e9rale fran\u00e7aise \u00e2g\u00e9e de 50 \u00e0 89 ans en 2020: Etude de cohorte prospective","idno":"FRESH-PEF5047-fr","producers":[{"name":"Vanina BONGARD","affiliation":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF5047-fr","IDno":{"metadata_no":[{"agency":"PEF","code":"5047"},{"agency":"FReSH","code":"FRESH-PEF5047"}]},"title":"Cohorte de sujets \u00e2g\u00e9s de 42 \u00e0 89 ans (en 2012)\/\u00e9tude du vieillissement c\u00e9r\u00e9bral et cardiovasculaire --> Evaluation de l\u2019impact des manifestations psycho-comportementales li\u00e9es au confinement lors de la pand\u00e9mie COVID-19 sur l\u2019aggravation des facteurs de risque cardiovasculaire et la d\u00e9compensation des maladies cardiovasculaires, en population g\u00e9n\u00e9rale fran\u00e7aise \u00e2g\u00e9e de 50 \u00e0 89 ans en 2020: Etude de cohorte prospective","alternate_title":"Mona Lisa - PREDOR: Prediction of Damage to Organs (2012) --> PSYCOV-CV (Etude COVID-19, 2020-2021)"},"study_authorization":{"agency":[{"name":"CNIL"},{"name":"CPP"}]},"authoring_entity":[{"type":"investigator","name":"Emilie;BERARD","PILabo":"CHU Toulouse \/ UMR1295 CERPOP, Equipe Vieillissement - Axe ARTERRE - Atherosclerosis Risk and Treatment Evaluation towards Risk Reduction Epidemiology","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","extlink":[{"title":"ORCID","uri":"0000-0001-5931-2971","role":"pi id"},{"title":"IdRef","uri":"238725936","role":"pi id"},{"title":"SIREN","uri":"263100125","role":"organisation id"},{"title":"RNSR","uri":"202124019W","role":"labo id"}],"email":"emilie.berard@univ-tlse3.fr","isContact":"Oui"},{"type":"investigator","name":"Vanina;BONGARD","PILabo":"CHU Toulouse \/ UMR1295 CERPOP, Equipe Vieillissement - Axe ARTERRE - Atherosclerosis Risk and Treatment Evaluation towards Risk Reduction Epidemiology","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","extlink":[{"title":"ORCID","uri":"0000-0001-5789-0815","role":"pi id"},{"title":"IdRef","uri":"058215573","role":"pi id"},{"title":"SIREN","uri":"263100125","role":"organisation id"},{"title":"RNSR","uri":"202124019W","role":"labo id"}],"email":"Vanina.bongard@univ-tlse3.fr","isContact":"Oui"}],"oth_id":[{"name":""}],"production_statement":{"prod_place":"Portail Epid\u00e9miologie France (PEF)","producers":[{"name":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/017h5q109","role":"sponsor id"},{"title":"SIREN","uri":"263100125","role":"sponsor id"}],"role":"sponsor"}],"funding_agencies":[{"name":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/017h5q109"},{"title":"SIREN","uri":"263100125"}]},{"name":"","extlink":[]},{"name":"","extlink":[]},{"name":"","extlink":[]}]},"distribution_statement":{"contact":[{"name":"Emilie;BERARD","email":"emilie.berard@univ-tlse3.fr","type":"contact","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/017h5q109","role":"organisation id","title":"ROR"},{"uri":"263100125","role":"organisation id","title":"SIREN"}]},{"name":"Vanina;BONGARD","email":"Vanina.bongard@univ-tlse3.fr","type":"contact","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/017h5q109","role":"organisation id","title":"ROR"},{"uri":"263100125","role":"organisation id","title":"SIREN"}]}]},"study_info":{"keywords":[{"keyword":"alt\u00e9ration"},{"keyword":"r\u00e9ponse aux tests psychom\u00e9triques et cognitifs"},{"keyword":"sept ans"},{"keyword":"pr\u00e9diction"},{"keyword":"facteurs pr\u00e9dictifs"},{"keyword":"risque cardiovasculaire + COVID-19"},{"keyword":"troubles de l\u2019humeur"},{"keyword":"confinement"},{"keyword":"maladies cardiovasculaires"},{"keyword":"facteurs de risque"},{"keyword":"population g\u00e9n\u00e9rale"}],"topics":[{"topic":"Cardiologie et m\u00e9decine vasculaire","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/4455c187-2f2f-4cd1-a4dd-449f59d73b39"},{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/c42fc6ec-b216-4a24-9e9d-f5e781c175a0"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D002309"}]},{"topic":"G\u00e9riatrie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/d37e4d8c-a978-40c7-ba4f-eee841851073"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D005853"}]},{"topic":"Neurologie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/c4793dfe-e80e-49dd-9fcc-a1a742de1b25"},{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/00a5c4f4-b7ee-41a4-bcdf-3a02e6be1660"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D009462"}]},{"topic":"COVID-19","vocab":"cim-11","extLink":[{"uri":"http:\/\/id.who.int\/icd\/entity\/1730556128","title":"CIM-11"}]},{"topic":"D\u00e9terminants socio-d\u00e9mographiques et \u00e9conomiques","vocab":"health determinant"},{"topic":"D\u00e9terminants comportementaux","vocab":"health determinant"},{"topic":"D\u00e9terminants comportementaux : Alimentation","vocab":"health determinant"}],"purpose":"Objectifs principaux : - Identifier les facteurs pr\u00e9dictifs d\u2019une alt\u00e9ration de la r\u00e9ponse aux tests psychom\u00e9triques et cognitifs et d\u2019une alt\u00e9ration du niveau de risque cardiovasculaire, sur une p\u00e9riode de sept ans. - D\u00e9velopper des formules de pr\u00e9diction du risque correspondantes. Objectifs secondaires : - Comparer la r\u00e9ponse aux tests psychom\u00e9triques et cognitifs en fonction de l\u2019\u00e2ge. - Estimer la pr\u00e9valence du syndrome de fragilit\u00e9 en fonction de l\u2019\u00e2ge. - Estimer la pr\u00e9valence de la d\u00e9pendance chez les sujets de plus de 60 ans. - Identifier les facteurs pr\u00e9dictifs de l\u2019apparition d\u2019un syndrome de fragilit\u00e9 ou d\u2019une d\u00e9pendance gr\u00e2ce au suivi mis en place \u00e0 partir de 2012. - Sur un sous-\u00e9chantillon de 500 sujets b\u00e9n\u00e9ficiant d\u2019une imagerie c\u00e9r\u00e9brale (PET-scan + IRM) : - Estimer la pr\u00e9valence de la pr\u00e9sence de d\u00e9p\u00f4ts amylo\u00efdes c\u00e9r\u00e9braux en population g\u00e9n\u00e9rale, en fonction de l\u2019\u00e2ge. - Quantifier l\u2019importance des d\u00e9p\u00f4ts amylo\u00efdes c\u00e9r\u00e9braux en fonction de l\u2019\u00e2ge. - D\u00e9crire le lien existant entre la pr\u00e9sence de d\u00e9p\u00f4ts amylo\u00efdes c\u00e9r\u00e9braux et la r\u00e9ponse aux tests psychom\u00e9triques et cognitifs. - Identifier les facteurs associ\u00e9s \u00e0 la pr\u00e9sence de d\u00e9p\u00f4ts amylo\u00efdes c\u00e9r\u00e9braux. Etude PSYCOV-CV: Objectif principal :Evaluation de l\u2019impact, en population g\u00e9n\u00e9rale fran\u00e7aise, des manifestations psycho-comportementales li\u00e9es au confinement lors de la pand\u00e9mie COVID-19 sur l\u2019aggravation des facteurs de risque cardiovasculaire et la d\u00e9compensation des maladies cardiovasculaires, pendant et apr\u00e8s la p\u00e9riode de confinement. Objectifs secondaires : 1. Description, et \u00e9valuation des d\u00e9terminants, des manifestations psycho-comportementales en r\u00e9ponse au confinement lors de la pand\u00e9mie COVID-19 en population g\u00e9n\u00e9rale fran\u00e7aise. 2. Evaluation de l\u2019impact des manifestations psycho-comportementales sur chacun des \u00e9l\u00e9ments suivants : aggravation de l\u2019\u00e9quilibre tensionnel, du profil m\u00e9tabolique ou lipidique, du poids, de l\u2019\u00e9quilibre alimentaire, diminution de l\u2019activit\u00e9 physique, majoration de la consommation tabagique, de toxiques (cannabis, coca\u00efne), d\u00e9compensation d\u2019une maladie cardiovasculaire, pendant et apr\u00e8s le confinement. 3. Evaluation des dynamiques de parcours de soins et de l\u2019impact \u00e9conomique en lien avec le confinement en \u00e9valuant la consommation de soins 12 mois avant la date du confinement, et 12 mois apr\u00e8s le confinement chez les patients inclus dans la cohorte PSYCOV-CV.","abstract":"","coll_dates":[{"start":"2012-01-01","end":"2021-01-01"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"['Occitanie']","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"Masculin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008297\"\n            }\n        },\n        {\n            \"value\": \"F\u00e9minin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Adulte (45 \u00e0 64 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008875\"\n            }\n        },\n        {\n            \"value\": \"Personne \u00e2g\u00e9e (65 \u00e0 79 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000368\"\n            }\n        },\n        {\n            \"value\": \"Grand \u00e2ge (80 ans et plus)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000369\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Population g\u00e9n\u00e9rale\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"Les sujets \u00e2g\u00e9s de 42 \u00e0 89 ans, des deux sexes, r\u00e9sidant en Haute Garonne, tir\u00e9s au sort sur listes \u00e9lectorales, et affili\u00e9s \u00e0 un r\u00e9gime de s\u00e9curit\u00e9 sociale ou \u00e9quivalent.  + PSYCOV-CV Tous les sujets (des deux sexes) \u00e2g\u00e9s de 50 \u00e0 89 ans en 2020, r\u00e9sidant en Haute Garonne, tir\u00e9s au sort sur listes \u00e9lectorales pour participer \u00e0 l\u2019enqu\u00eate en population g\u00e9n\u00e9rale Mona Lisa en 2005 et ayant accept\u00e9 de participer \u00e0 l'\u00e9tude PSYCOV-CV.\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Donn\u00e9es cliniques','Donn\u00e9es rapport\u00e9es par le participant de l'\u00e9tude','Donn\u00e9es paracliniques','Donn\u00e9es biologiques','Donn\u00e9es socio-d\u00e9mographiques','Donn\u00e9es \u00e9conomiques','Donn\u00e9es paracliniques (hors biologiques) : Autre']","quality_statement":{"standards":[{"name":"","committee":"","governance":""}],"other_quality_statement":""}},"study_development":{"development_activity":[{"activity_type":"primary 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SNDS)","collectionModeOther":""},"dataCollection":{"inclusionStrategyOther":"","samplingModeOther":"","recruitmentSourceOther":"","otherDocumentation":""},"dataCollectionIntegration":{"isDataIntegration":"Oui"},"geographicalCoverage":{"geoDetail":"Haute-Garonne"},"dataTypes":{"clinicalDataDetails":"--","biologicalDataDetails":"glyc\u00e9mie, h\u00e9moglobine A1c, bilan lipidique, cr\u00e9atinin\u00e9mie, transaminases, insulin\u00e9mie, ECG,mesure de la masse grasse","isDataInBiobank":"Oui","biobankContent":[],"biobankContentOther":"","dataTypeOther":""},"variableDictionnary":{"variableDictionnaryAvailable":"","variableDictionnaryLink":""},"dataQuality":{"otherDocumentation":""},"mockSample":{"mockSampleAvailable":"","mockSampleLocation":""},"thirdPartySource":{"otherSourceType":[""]},"isHealthTheme":"Oui","fileDscr":{"fileTxt":{"fileCitation":{"titlStmt":{"IDno":[]}}}}},"schematype":"survey"}