<?xml version="1.0" encoding="UTF-8"?>
<codeBook version="2.5" ID="FReSH-61023-en" xml-lang="en" xmlns="ddi:codebook:2_5" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="ddi:codebook:2_5 https://ddialliance.org/Specification/DDI-Codebook/2.5/XMLSchema/codebook.xsd">
<docDscr>
  <citation>
    <titlStmt>
      <titl>Acute Effects of Neurodynamic Stretching on Muscle-tendon Complex</titl>
      <IDNo>FReSH-61023-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="UNIVERSITE BOURGOGNE EUROPE" role="">Lesya BAUDOIN</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Acute Effects of Neurodynamic Stretching on Muscle-tendon Complex            </titl>
      <altTitl>
                    ELASTRETCH                </altTitl>
      <IDNo agency="FReSH-lang">
                FReSH-61023-en            </IDNo>
      <IDNo agency="ClinicalTrials">
                    NCT07304765                </IDNo>
      <IDNo agency="sponsor">
                    CEP2204                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Andréa BLIVET                                                <ExtLink title="ORCID" URI="null" role="pi id"/>
                                                                                                                    <ExtLink title="IdRef" URI="null" role="pi id"/>
                                                                                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE BOURGOGNE EUROPE">
        <ExtLink title="SIREN" URI="null" role="organisation id"/>
        <ExtLink title="ROR" URI="https://ror.org/00g700j37" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
        <ExtLink title="RNSR" URI="null" role="labo id"/>
      </AuthEnty>
      <othId affiliation="" type="contributor">
        <ExtLink title="ORCID" URI="" role="team member id"/>
        <ExtLink title="IdRef" URI="" role="team member id"/>
      </othId>
      <othId affiliation="" type="affiliation">
        <ExtLink title="RNSR" URI="" role="labo id"/>
      </othId>
      <othId affiliation="" type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            UNIVERSITE BOURGOGNE EUROPE                    
                                    </producer>
      <prodPlac>
                France Recherche en Santé Humaine (FReSH)            </prodPlac>
      <fundAg>
                                            GIS-INSTITUT POUR LA RECHERCHE EN SANTE PUBLIQUE (IRESP)                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="UNIVERSITE BOURGOGNE EUROPE" email="andrea.blivet@inserm.fr">
                    Andréa;BLIVET
                                            <ExtLink title="SIREN" URI="" role="organisation id"/>
                                            <ExtLink title="ROR" URI="https://ror.org/00g700j37" role="organisation id"/>
                                            <ExtLink title="RNSR" URI="" role="labo id"/>
                                    </contact>
      <depDate date="2026-07-03"/>
      <distDate date="2026-07-03"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <studyAuthorization>
    <authorizingAgency>CPP                </authorizingAgency>
  </studyAuthorization>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <topcClas vocab="health theme">
                        Emergency medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/5e1591e2-d02b-436c-8216-6b8912eee467"/>
                                                            <ExtLink title="MeSH" URI="D004635"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Physical and Rehabilitation Medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/38e57437-b2cc-4d26-a46e-c5b639c01e5f"/>
                                                            <ExtLink title="MeSH" URI="D010810"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Sports medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/ff9e9276-586f-44d1-a309-368cbd77bdcb"/>
                                                            <ExtLink title="MeSH" URI="D013178"/>
                                                </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants: Other                    </topcClas>
      <topcClas vocab="other biological determinant">
                        physical condition                    </topcClas>
    </subject>
    <abstract contentType="purpose">Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves. Two main approaches are distinguished. Nerve tensioning and nerve flossing. They both involve proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings on neurodynamic techniques highlighted the current lack of consensus regarding these techniques. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Accordingly, the primary objective of the present study was to determine the immediate effect of two neurodynamic mobilization techniques (flossing vs. tensioning) on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).</abstract>
    <abstract contentType="abstract">Neurodynamic mobilization techniques are frequently applied in rehabilitation settings to enhance the mobility and function of peripheral nerves, particularly in the management of neuropathic pain such as carpal tunnel syndrome, radiculopathies, or sciatica. Two main approaches are distinguished. Nerve tensioning involves maintaining the nerve stretched at the end of the joint range of motion with relatively limited excursion. It is similar to a static stretching intervention but with distal (ankle) and proximal (cervical) tensions. Nerve flossing (also termed gliding or sliders), consists of alternating proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings on neurodynamic techniques highlighted the current lack of consensus regarding the acute effects of the different possible neurodynamic techniques on sciatic nerves, particularly in healthy tissues. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Performed in patients, healthy or athletes, no study has compared both tensioning or flossing techniques. Moreover, because these techniques involved nerve mobilisation, the intensity should have a main effect of its efficiency. Accordingly, the primary objective of the present study was to determine the immediate effect of two neurodynamic mobilization techniques (flossing vs. tensioning) on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE). This method has been shown reliable to provide non-invasive real-time assessments of soft tissues elastic properties. The secondary aim was to determine the effects of stretching intensity (at the point of pain threshold or below).</abstract>
    <sumDscr>
      <collDate event="start" date="2025-02-01"/>
      <collDate event="end" date="2025-12-26"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individus            </anlyUnit>
      <universe level="type" clusion="I">General population                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="D005260"/>
                                                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Other                                                            <concept vocab="MeSH"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="D055815"/>
                                                    </universe>
      <universe level="age" clusion="I">Adult (25 to 44 years)                                                            <concept vocab="MeSH" vocabURI="D000328"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="D008875"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged (65 to 79 years)                                                            <concept vocab="MeSH" vocabURI="D000368"/>
                                                    </universe>
      <universe clusion="I">healthy
physical active
no injuries (lower limb or back pain) in the past 3 months                    </universe>
      <universe clusion="E">Specific lower limb (hamstring) injuries in the past 2 years
Not restraining activity 24h before participation                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Paraclinical data (non-biological)</dataKind>
      <dataKind>Paraclinical data (non-biological) : Imaging</dataKind>
      <dataKind>Paraclinical data (non-biological) : Function testing</dataKind>
    </sumDscr>
    <qualityStatement>
      <standardsCompliance>
        <standard>
          <producer role="other governance">Faculty scientific council                                </producer>
        </standard>
      </standardsCompliance>
    </qualityStatement>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Nerve shear wave velocity using elastography</description>
    </developmentActivity>
    <developmentActivity type="secondary evaluation">
      <description>Muscle shear wave velocity using elastography
Hamstring force
Biceps femoris activity
passive knee extension
Global flexibility</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <frequenc>once</frequenc>
      <sampProc>Non-probability                                                            <concept vocab="CESSDA" vocabURI="Nonprobability"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Other</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>&lt; 500 individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Experiment / trial                                                            <concept vocab="CESSDA" vocabURI="Experiment"/>
                                                    </collMode>
      <collMode>Laboratory experimentation (controlled conditions)                                                            <concept vocab="CESSDA" vocabURI="Experiment.Laboratory"/>
                                                    </collMode>
      <sources>
        <sources>
          <sourceCitation>
                                    
                                    
                                                                    </sourceCitation>
        </sources>
      </sources>
    </dataColl>
    <notes>Interventional Study</notes>
    <notes subject="research type">
                        Interventional Study                    </notes>
    <notes subject="follow-up">
                        Monitoring by participant visit to the investigation center                    </notes>
    <anlyInfo>
      <respRate>21</respRate>
    </anlyInfo>
    <stdyClas>Completed study</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <accsPlac>
                            website                        </accsPlac>
      <avlStatus>
                            Open access                                                            <ExtLink title="COAR" URI="http://purl.org/coar/access_right/c_abf2"/>
                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <contact email="andrea.blivet@inserm.fr">Andréa;BLIVET</contact>
      <conditions>data freely available in online websites</conditions>
    </useStmt>
  </dataAccs>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
