{"doc_desc":{"title":"Acute Effects of Neurodynamic Stretching on Muscle-tendon Complex","idno":"FReSH-61023-en","producers":[{"name":"Lesya BAUDOIN","affiliation":"UNIVERSITE BOURGOGNE EUROPE"}]},"study_desc":{"title_statement":{"idno":"FReSH-61023-en","IDno":{"metadata_no":[{"agency":"ClinicalTrials","code":"NCT07304765"},{"agency":"sponsor","code":"CEP2204"}],"metadata_yes":[{"code":"FReSH","agency":"FReSH"}]},"uri":null,"title":"Acute Effects of Neurodynamic Stretching on Muscle-tendon Complex","alternate_title":"ELASTRETCH"},"study_authorization":{"agency":[{"name":"CPP"}]},"authoring_entity":[{"name":"Andr\u00e9a;BLIVET","firstname":"Andr\u00e9a","lastname":"BLIVET","type":"investigator","extlink":[{"title":"ORCID","uri":"","role":"pi id"},{"title":"IdRef","uri":"","role":"pi id"},{"title":"SIREN","uri":"","role":"organisation id"},{"title":"ROR","uri":"https:\/\/ror.org\/00g700j37","role":"organisation id"},{"title":"RNSR","uri":"","role":"labo id"}],"email":"andrea.blivet@inserm.fr","affiliationName":"UNIVERSITE BOURGOGNE EUROPE","PILabo":"Universite Bourgogne Europe - faculty of sports sciences","isContact":"Yes"}],"oth_id":[{"name":";","firstname":"","lastname":"","type":"contributor","isContact":"","extlink":[{"title":"ORCID","uri":"","role":"team member id"},{"title":"IdRef","uri":"","role":"team member id"}]},{"name":"","type":"affiliation","teamMemberLabo":"","extlink":[{"title":"","uri":"","role":"organisation id"},{"title":"RNSR","uri":"","role":"labo id"}]},{"name":"","type":"collaboration"}],"production_statement":{"prod_place":"France Recherche en Sant\u00e9 Humaine (FReSH)","producers":[{"name":"UNIVERSITE BOURGOGNE EUROPE","role":"sponsor","extlink":[{"title":"SIREN","uri":"938230612","role":"sponsor id"},{"title":"ROR","uri":"https:\/\/ror.org\/00g700j37","role":"sponsor id"}]}],"funding_agencies":[{"name":"GIS-INSTITUT POUR LA RECHERCHE EN SANTE PUBLIQUE (IRESP)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/05fw72335"}]}]},"distribution_statement":{"contact":[{"name":"Andr\u00e9a;BLIVET","lastname":"BLIVET","firstname":"Andr\u00e9a","type":"contact","email":"andrea.blivet@inserm.fr","affiliationName":"UNIVERSITE BOURGOGNE EUROPE","contactPointLabo":"Universite Bourgogne Europe - faculty of sports sciences","extlink":[{"title":"SIREN","uri":"","role":"organisation id"},{"title":"ROR","uri":"https:\/\/ror.org\/00g700j37","role":"organisation id"},{"title":"RNSR","uri":"","role":"labo id"}]}]},"study_info":{"keywords":[],"topics":[{"topic":"Emergency medicine","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/5e1591e2-d02b-436c-8216-6b8912eee467"},{"title":"MeSH","uri":"D004635"}],"vocab":"health theme"},{"topic":"Physical and Rehabilitation Medicine","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/38e57437-b2cc-4d26-a46e-c5b639c01e5f"},{"title":"MeSH","uri":"D010810"}],"vocab":"health theme"},{"topic":"Sports medicine","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/ff9e9276-586f-44d1-a309-368cbd77bdcb"},{"title":"MeSH","uri":"D013178"}],"vocab":"health theme"},{"topic":"Biological determinants","vocab":"health determinant"},{"topic":"Biological determinants: Other","vocab":"health determinant"},{"topic":"physical condition","vocab":"other biological determinant"}],"purpose":"Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves. Two main approaches are distinguished. Nerve tensioning and nerve flossing. They both involve proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings on neurodynamic techniques highlighted the current lack of consensus regarding these techniques. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Accordingly, the primary objective of the present study was to determine the immediate effect of two neurodynamic mobilization techniques (flossing vs. tensioning) on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).","abstract":"Neurodynamic mobilization techniques are frequently applied in rehabilitation settings to enhance the mobility and function of peripheral nerves, particularly in the management of neuropathic pain such as carpal tunnel syndrome, radiculopathies, or sciatica. Two main approaches are distinguished. Nerve tensioning involves maintaining the nerve stretched at the end of the joint range of motion with relatively limited excursion. It is similar to a static stretching intervention but with distal (ankle) and proximal (cervical) tensions. Nerve flossing (also termed gliding or sliders), consists of alternating proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings on neurodynamic techniques highlighted the current lack of consensus regarding the acute effects of the different possible neurodynamic techniques on sciatic nerves, particularly in healthy tissues. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Performed in patients, healthy or athletes, no study has compared both tensioning or flossing techniques. Moreover, because these techniques involved nerve mobilisation, the intensity should have a main effect of its efficiency. Accordingly, the primary objective of the present study was to determine the immediate effect of two neurodynamic mobilization techniques (flossing vs. tensioning) on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE). This method has been shown reliable to provide non-invasive real-time assessments of soft tissues elastic properties. The secondary aim was to determine the effects of stretching intensity (at the point of pain threshold or below).","coll_dates":[{"start":"2025-02-01","end":"2025-12-26"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"D005260\"\n            },\n            \"value\": \"Female\"\n        },\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"D008297\"\n            },\n            \"value\": \"Male\"\n        },\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"\"\n            },\n            \"value\": \"Other\"\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"D055815\"\n            },\n            \"value\": \"Young Adult (19 to 24 years)\"\n        },\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"D000328\"\n            },\n            \"value\": \"Adult (25 to 44 years)\"\n        },\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"D008875\"\n            },\n            \"value\": \"Middle Aged (45 to 64 years)\"\n        },\n        {\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"D000368\"\n            },\n            \"value\": \"Aged (65 to 79 years)\"\n        }\n    ],\n    \"level_type_clusion_I\": \"General population\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"healthy\\r\\nphysical active\\r\\nno injuries (lower limb or back pain) in the past 3 months\",\n    \"clusion_E\": \"Specific lower limb (hamstring) injuries in the past 2 years\\r\\nNot restraining activity 24h before participation\"\n}","data_kind":"['Clinical data','Paraclinical data (non-biological)','Paraclinical data (non-biological) : Imaging','Paraclinical data (non-biological) : Function testing']","quality_statement":{"standards":[{"name":"","committee":"","governance":"Faculty scientific council"}],"other_quality_statement":""}},"study_development":{"development_activity":[{"activity_type":"primary evaluation","activity_description":"Nerve shear wave velocity using elastography"},{"activity_type":"secondary evaluation","activity_description":"Muscle shear wave velocity using elastography\r\nHamstring force\r\nBiceps femoris activity\r\npassive knee extension\r\nGlobal flexibility"}]},"method":{"data_collection":{"time_method":"","frequency":"once","sampling_procedure":"['{\"concept\":{\"vocab\":\"CESSDA\",\"vocabURI\":\"Nonprobability\"},\"value\":\"Non-probability\"}']","sample_frame":{"frame_unit":{"unit_type":"['Other']"}},"coll_mode":["{\"concept\":{\"vocab\":\"CESSDA\",\"vocabURI\":\"Experiment\"},\"value\":\"Experiment \/ trial\"}","{\"concept\":{\"vocab\":\"CESSDA\",\"vocabURI\":\"Experiment.Laboratory\"},\"value\":\"Laboratory experimentation (controlled conditions)\"}"],"research_instrument":"","sources":[{"sourceCitation":{"titlStmt":{"titl":""},"holdings":"","notes":{"subject":"source purpose","value":""}},"srcOrig":[]}],"target_sample_size":"< 500 individuals","response_rate":"21"},"method_notes":"Interventional Study","study_class":"Completed study","notes":[{"subject":"research type","values":["Interventional Study"]},{"subject":"follow-up","values":["Monitoring by participant visit to the investigation center"]}]},"data_access":{"dataset_availability":{"access_place":"website","complete":"","status":"{\"extLink\":{\"title\":\"COAR\",\"uri\":\"http:\/\/purl.org\/coar\/access_right\/c_abf2\"},\"value\":\"Open access\"}"},"dataset_use":{"restrictions":"","conditions":"data freely available in online websites","conf_dec":[{"txt":""}],"spec_perm":[{"txt":"","required":"No"}],"contact":[{"name":"Andr\u00e9a;BLIVET","firstname":"Andr\u00e9a","lastname":"BLIVET","email":"andrea.blivet@inserm.fr"}],"deposit_req":"","cit_req":""},"notes":""}},"additional":{"IsImport":false,"versionLang":"en","originLang":"en","lastUpdatedAuto":"03-04-2026","lastUpdatedManual":"03-04-2026","autoTranslation":false,"status":"Awaiting validation","respValidation":"","isHealthTheme":"Yes","isContributorPI":"No","addTeamMember":"No","primaryInvestigator":{"isPIContact":"Yes","piMail":"andrea.blivet@inserm.fr","piAffiliation":{"piLabo":"Universite Bourgogne Europe - faculty of sports sciences"}},"relatedDocument":[{"type":"","title":"","link":""}],"contactPointLabo":"Universite Bourgogne Europe - faculty of sports sciences","obtainedAuthorization":{"otherAuthorizingAgency":[""]},"regulatoryRequirements":{"conformityDeclaration":""},"fundingAgent":{"fundingAgentType":["Public (France)"],"otherFundingAgentType":[""]},"sponsor":{"sponsorType":["Public (France)"],"otherSponsorType":[""]},"governance":{"committee":"Other"},"collaborations":{"networkConsortium":"No"},"theme":{"complementaryInformation":"","RareDiseases":"No"},"interventionalStudy":{"researchPurpose":["Other"],"trialPhase":["NA"],"interventionalStudyModel":"Crossover","isClinicalTrial":"Yes","otherResearchPurpose":""},"isInclusionGroups":"No","allocation":{"allocationMode":"Randomised","allocationUnit":"Individual"},"masking":{"maskingType":"Blinded","blindedMaskingDetails":["Outcomes Assessor"]},"arms":[{"name":"Control","type":"No intervention","typeOther":"","description":"Seated at rest during the same duration than the interventions"},{"name":"Static stretching at pain threshold","type":"Active Comparator","typeOther":"","description":"Static stretching at pain threshold of the right hamstring muscles 5x60s with 20s rest"},{"name":"Neurodynamic tensioning at pain threshold","type":"Experimental","typeOther":"","description":"Neurodynamic tensioning of the right hamstring muscles 5x60s with 20s rest at pain threshold"}],"intervention":[],"cohortLongitudinal":{"recrutementTiming":[]},"otherResearchType":{"otherResearchTypeDetails":""},"inclusionGroups":[],"nrInclusionGroups":false,"collectionProcess":{"collectionModeDetails":"","collectionModeOther":""},"dataCollection":{"inclusionStrategy":[],"inclusionStrategyOther":null,"samplingModeOther":"","recruitmentSourceOther":"advertisement","otherDocumentation":""},"activeFollowUp":{"isActiveFollowUp":"Yes","followUpModeOther":""},"dataCollectionIntegration":{"isDataIntegration":"No"},"geographicalCoverage":{"geoDetail":""},"dataTypes":{"clinicalDataDetails":"neurodynamic mobilization techniques (flossing vs. tensioning) ","biologicalDataDetails":"","isDataInBiobank":null,"biobankContent":[],"biobankContentOther":"","dataTypeOther":"","paraclinicalDataOther":"","otherLiquidsDetails":""},"variableDictionnary":{"variableDictionnaryAvailable":"No","variableDictionnaryLink":""},"dataQuality":{"otherDocumentation":""},"mockSample":{"mockSampleAvailable":"No","mockSampleLocation":""},"thirdPartySource":{"otherSourceType":[""]},"fileDscr":{"fileTxt":{"fileCitation":{"titlStmt":{"IDno":[{"type":"","uri":""}]}}}}},"schematype":"survey"}